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Vol. 1 · Ed. 2026
CyberGlossary
Entry № 725

Next-Generation Antivirus (NGAV)

What is Next-Generation Antivirus (NGAV)?

Next-Generation Antivirus (NGAV)Endpoint protection that augments signature scanning with machine-learning models, behavioral analytics, and exploit prevention to stop unknown and fileless threats.


Next-Generation Antivirus (NGAV) emerged in the mid-2010s in response to the limits of signature-only AV. Vendors such as CrowdStrike Falcon, SentinelOne Singularity, Microsoft Defender for Endpoint, VMware Carbon Black, and Cybereason combine cloud-trained ML classifiers, behavioral monitors that watch process and API telemetry, exploit-mitigation modules, and Indicator-of-Attack (IOA) detection. NGAV blocks fileless techniques like LOLBins and reflective DLL loading that bypass classical signatures, and is the prevention layer typically packaged with an EDR or XDR sensor. NIST SP 800-83 and the MITRE Engenuity ATT&CK Evaluations describe and benchmark this category. Effective NGAV reduces dwell time but requires tuning to control false positives in developer-heavy environments.

Examples

  1. 01

    CrowdStrike Falcon Prevent blocking a previously unseen ransomware binary based on behavioral patterns instead of a signature.

  2. 02

    Microsoft Defender ASR rule preventing Office macros from spawning child processes.

Frequently asked questions

What is Next-Generation Antivirus (NGAV)?

Endpoint protection that augments signature scanning with machine-learning models, behavioral analytics, and exploit prevention to stop unknown and fileless threats. It belongs to the Defense & Operations category of cybersecurity.

What does Next-Generation Antivirus (NGAV) mean?

Endpoint protection that augments signature scanning with machine-learning models, behavioral analytics, and exploit prevention to stop unknown and fileless threats.

How does Next-Generation Antivirus (NGAV) work?

Next-Generation Antivirus (NGAV) emerged in the mid-2010s in response to the limits of signature-only AV. Vendors such as CrowdStrike Falcon, SentinelOne Singularity, Microsoft Defender for Endpoint, VMware Carbon Black, and Cybereason combine cloud-trained ML classifiers, behavioral monitors that watch process and API telemetry, exploit-mitigation modules, and Indicator-of-Attack (IOA) detection. NGAV blocks fileless techniques like LOLBins and reflective DLL loading that bypass classical signatures, and is the prevention layer typically packaged with an EDR or XDR sensor. NIST SP 800-83 and the MITRE Engenuity ATT&CK Evaluations describe and benchmark this category. Effective NGAV reduces dwell time but requires tuning to control false positives in developer-heavy environments.

How do you defend against Next-Generation Antivirus (NGAV)?

Defences for Next-Generation Antivirus (NGAV) typically combine technical controls and operational practices, as detailed in the full definition above.

What are other names for Next-Generation Antivirus (NGAV)?

Common alternative names include: NGAV, Next-gen AV.

Related terms

See also